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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '28cfbef23b1f75c41560b0ddec92f68c85ecdb52df92b18288416c6fc1679b4b' 
  AND token = 'OHUq+bJF8kWUZFOIQsMdjB1FDKEU9aqYe0n+PrMgvIU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}