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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5331d8b620495c47e7be0c5b3e229bc40b07ea4df5370e7cce5908d27623c247' 
  AND token = 'sWHVsIp1P7s7zzqVblZrEKEa1niYHF2M3MCxuo5SU58=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}