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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4400d5c6d1168d82b3ba144fada8e26c7ca4000f6f6e86c388d5ab62df0037f8' 
  AND token = 'TLOMdTioyHMaxrMk+y4N+1K2NrqqIahpeBO73lF4UEw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}