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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '919c0d62c07c3f816cc92d80befc660c8afbf36e5b5d9fdb742a71a4b1fb82f1' 
  AND token = 'z5WKT8W/s+X/31cKVdEt7aXqsHZTV2Oz7o0YBJuXwEc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}