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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e70fa24777b0503665c79dea8a8ed9c0259f030c2f6d102c26dee8f817bfdec' 
  AND token = 'Q5GYY+SM22UK6YoePAciesjAHUzcmHLq0df2kOp7w4A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}