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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '163609bd68d32f0abc3e9277573de95a7cdb321cab0801ad9c142ebab9b38433' 
  AND token = 'sNqJpY3pjZ5Ar0vJ1R4qaNW4ujROI9IeZB5mJcjf7tc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}