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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b8eef4f3971193a4c4d14ef907a2430ba7c08264973df3bde3bd024c40651540' 
  AND token = 'MVKP5i1vAv9QMzGX37kp/Qdg9OhVlGQMSleztfVHlNQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}