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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '601f8ad5459911a42aa3d78e08f4b0fab13deac5276c1fbccb822232a6d5ba2b' 
  AND token = 'hnYZoG9YtsQ22OV+xWE43BwsTvEWEM42tEys6rgPD2g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}