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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '261826f97c1d1432304558a8c9d2bca99b0134b88d5430ddf3086ac35cc8a3bc' 
  AND token = 'Lyaxd+naBSPfwMeXUifUC0SgWJj3Iah56e4nyf9mN6M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}