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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1f2fff2b0e2def34a3a21727e9243e99aebca90c53b7ee629465a1496076c6b2' 
  AND token = 'qqKZMqWtpvQEuvVPiwVW0JkRxEMxpFtQtF7p/0ENBnA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}