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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b9c6ee3ea1205fd7f2db550f48038526ebbea6230f0b0751649c68e3dc242dd' 
  AND token = '5sQdWonXQzEN6osFcSWUtXT7RRDkvguwW5PZCwtA3Cs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}