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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41dde4a4819a5eaf2b795a0c1161ee3e0426988ae2a158819359e4229a4bf033' 
  AND token = 'jsXsMDkkdJy6CydS5LFaHhoHfpXcMi75nerOjGNfmBo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}