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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4eb0202e4f160c1515be16b517c725c00ca8b7ea4890f15c525b1384168692e2' 
  AND token = '/ZQ37AuybxQkSwDFq0HQu897VdidjAb/zW9wL22UQfo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}