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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a717434a3a9504a5d55406d816b30fc5b27821a726ff9d2438930fc05f37cc25' 
  AND token = '8VR4jPQ/mzmtUW7gxkgQ3uk4M0shg0ahDPAs5kWFVho=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}