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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd6c75c4c2fe2d878fb0e937cfd3eda272c62b7206e997157254b3bb43ae5fc80' 
  AND token = 'o7pN/+aagUwC6gSVU5QuobtEY23Jr4/7zFfZMpFW5lM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}