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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '261260a7b1c97bab5d0c67190ebb23acfd26cb8af0233cf61a44403be482b443' 
  AND token = 'VF/35b53b/JWm+vFq/zsCa/uoQUx8xjyWtz3WFNIv8U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}