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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b3721aeccef26e505399b415e04374944abe94ed3a3378252f5f29bd1de66b72' 
  AND token = 'udh9bi/leQL1RuwV/WDUlIk/AC2smmSma9Jq73/zrEI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}