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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e09b16be9fbbe3864fdd90eb2640770c10fed2ed591c3c235b202baed84e6cda' 
  AND token = '5TZ6f5HP+VtiJqf1eXmw1BxpffBdlPHKa2FSybVc2Ss=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}