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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a0edad9a56d75096b9249fccbf4d5e1413dc9eebb455e973c01d9ed14321e485' 
  AND token = '+AeIb7Gs0Zadi8AATWZOq3Y7rkdaIoAhHsnjzq28+so=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}