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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b1c68c156aae9ab547cfad27461a1ecc82f30509c28861627832909b31627400' 
  AND token = 'M5v05tD7WrWThGWuneXZzYedW5WRSd7R96aLkiTVIpE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}