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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '133ff620637031c18a8c4caeb9159f9d68cdcc81a9849fadd5e66ed411ff9a20' 
  AND token = '9qY8Cx8iBziMRvRs9nn1n7MmCZ2Wm8txzSX5sbR2e44=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}