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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66bf922129d89249165c29f6976aa191ba72f50f4f624651d2887404f9e11072' 
  AND token = 'KdVZjjCdthNUP5R9yLTe4iRI8vH5T3mDOpRW7LQeh5M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}