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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a21954735e63f9df0d662911db9d82ac33bac4daf5c1fe6df907c8fb4af85b4e' 
  AND token = 'B4Rjroc0jnsmVLgi54yMOqCS5V5v2+9TFyB7nPFd/C0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}