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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '901f5e53683131de390761fc44778d8c4a491174f529d15c70c29e4f5a8bb331' 
  AND token = 'ptjjuuO+jAq9k9rp3tgZit0U9YrCdYKBOO/+rZ+bbxQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}