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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'efa73b19dadda0a3301440577c44991235d270d04445b4cbefb01a8215cfe6ed' 
  AND token = 'F7HGeEGTYGsuWVJR20UEsHgBHG16fhS9uS4Y6aCqStg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}