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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10a29d0317ba1e3d5b251e87193eeb3923ee81cc1a561c4e7e0adcec3bb70589' 
  AND token = '13N2p99V/My2rXRXeSnD6cUVGqwaEanVKyPo8mRwB94=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}