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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '152bb19ba47b08a56cb7bef42b6501c45d1cc7b04a6f3d7e4b6ae84594d78773' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}