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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '57f8ce580c015dc864d62bab30c1d5d1ddfaedb574647f132b432e6aa211c9f5' 
  AND token = 'ILQyvPvuEwYGr5RhloEbGMZRMjCiho3VAQXdQe01IGE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}