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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dc7e25ca3b08eb498e565cecc7d4fb1cf235ed8c018f671fc42477403f4078e5' 
  AND token = '16djTRmlmnFBdWe2kC77raztGOLLhoybyqeLm4EQdNY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}