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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c7bcacffe5d8155d3d7f8aecdc06482699dd03b2f87f843ffd84f1033744673' 
  AND token = 'ROzW8ckv5Hy2ov+Dr67G6fTwXI0Zq4a2HZ7igyd60kM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}