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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af01e682614a40a890ffaf8e064e23db8a1c7b17b364ad5697db389c3b344e6b' 
  AND token = '2jMR8kufjrFbymarnU8YFsmRTWUJiGQvZaqCBkmOWr8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}