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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b7144caf696f5c82bc4c9222bf9c388112c3cd1e4724d7f097f9dd6fe29e270' 
  AND token = 'gVe0h9uW6vo5T+kK4+08cqG1GytGIELykA4JM02WNE0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}