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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0801097e21953431da6cf5cb533af0f91123bfddc4f9b782322bc3bb7f576855' 
  AND token = 'ERJ/OrZ4JFGchgeC4tWO1SCuA/HH4u91ageFqZFdfwE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}