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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9557e78291fd5e702f06994317ee3e9a29af4a601ad1d9d361eb49316659d845' 
  AND token = '367IYuFVqqUiv1q7ZTfqTPXYr40UZstKNf0rwrLicuE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}