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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f67f212e1ee2b476eee8d5d7d27ea0f552274ba95df2ed95c555ff2c838a256' 
  AND token = '79XCBwZCQZBc9gPiwCm9SrUeKKDrrwgzpCDFXe2MxEs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}