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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b8c7e7c005d7544b8b39f161f7a63c238c7fc72af40c5c9ce2b40e91d44f3603' 
  AND token = 'EFjd5BboZLQvl7gascPMtXgjmqX0UcuwsNcoKh7DiRM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00058

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}