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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'efb0ff9ef32b130918dfb1d756da0cfa4f16b8813626a7d496399d8118324f25' 
  AND token = 'KYmy4gQMomQ7MTaVvoSMBi4vHYhrPFQclEb4O44Fi3c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}