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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0357ac688404b7df37e6d4f3ba2554d808012894eb5e1eea65643ead0495f5a9' 
  AND token = '8zeB8MI4e7kULPo8sX/qabZGC5cywllMY+oNVLYOVIc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}