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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '26a51c46c05c0add5d841daeba6972d364d134682b7f5de418ecd49f3bac4a0a' 
  AND token = '0kGsphYQqLgaYCcuDNyjAqOuXIARsJcxrTgkPEKELKE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}