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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '23a2dfb85c61683417a261c8c4326b1bb266ef03af6426cfa347f8cacebe8d80' 
  AND token = 'SENsKOoBq+12Vn3C+FCBGCO9bHZvoeZE4/OTOFYJ/eM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}