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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '61531b0bdc38de9da6b396255ca20ae3e2b513da4e8c08c5862020f5ac4ba8e4' 
  AND token = 'OhoCOc+OiCvJqPXNQfN0KpeJh3Vbkp9bKzXL34NOkm4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}