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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bc650c21bc7bc2d290767d757c029426e350a60c36c96281f8cc2a779fe82d56' 
  AND token = 'ruqzf3xaGDO2IdkGA8oejBOROUkfKUTCoWml1H7n6v0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}