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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '20b9dff35db3e605fa3ce39748080f36701b83e1fab13671f5cf610f8e5fc0ae' 
  AND token = 'DAoDEwoHeGmFLVvPYhQ35nTqdKkmuB5Y0vosArOivCQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}