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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f2db2323ec950a37dd26727658cd77f871d462668cd9fc4015d3c7a351bb0da7' 
  AND token = 'rJCKpno2GAA+S+ceOAnadNM/PKR2tADSsYrq7XFE2Rk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}