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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'be21f1ab502a4c25e7ded3043e4fd4b0d2c7e7119814ac053eb1f00deca4622f' 
  AND token = 'EqmNbfBHy6pfN00mMUGu3kIK9XXycLh4sb4YH1mji/Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}