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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '003c082ef936cddc448f89f0126703075442fe621427e68841edf51f315a0396' 
  AND token = 'ZgGH1cvlWOyo6uh9bg2W6ND7hCuRoFk6up3P4k0F4Ow=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}