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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a6784bfd40922d7865d9abe3d1264d7c1ef38f40457440ee395ea5fb2570f3ef' 
  AND token = 'Fafqqh0c+JWWRmNaETt+9aPOwhu71Lr+VOaAqA4DAHA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}