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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b4c99bb4dd029396330bdfc75a8d6a8bf6428ebaaa570963f452e8eeec983827' 
  AND token = 'xxEg3Qf6Ly9HqHVYI50uy+fv4R07s7KBVmRMVdOi2pY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}