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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '260482948ab36521b960bebab8789462a349dec04d0ef44222453322b618f88c' 
  AND token = 'HaAmLB+A2TuQqRjBcurJqVR9kRl80ngCVVuwo1OXxaY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}