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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd1d32d63bc584d9ad7b106a32c68aa888ba5c54bb708f819dad8630660cfd483' 
  AND token = 'SNalbTSdzpzZqs5/qlHQy4sKPM2Y62Tq56y29dCm4oM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}